DEFINING THE TEMPORAL RELATIONSHIP BETWEEN THE SKIN MICROBIOME, IMMUNE RESPONSE AND SKIN BARRIER FUNCTION DURING FLARE AND RESOLUTION OF ATOPIC DERMATITIS: PROTOCOL OF A DANISH INTERVENTION STUDY

Introduction Lesional skin of atopic dermatitis (AD) is often colonised by Staphylococcus aureus and the bacterial abundance increases during a flare.However, the role of S.aureus and the skin microbiome in the pathogenesis of AD, including its influence on the dysfunctional skin barrier and immune response, remains to be elucidated.In this study,

The concept of closed nuclear fuel cycle seems to be the most promising options for the efficient usage of the nuclear energy resources.However, it can be implemented only in fast breeder reactors of the IVth generation, which are characterized by the fast neutron spectrum.The lead-cooled fast 9.5-4 igora vibrance reactor (LFR) was defined and stud

A Bayesian random effects modeling approach was used to examine the influence of neighborhood characteristics on burglary risks in Jianghan District, Wuhan, China.This random effects model is essentially spatial; a spatially structured random effects term and an unstructured random effects term are added to the traditional non-spatial Poisson regre